Connecticut Asthma & Allergy Center

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Allergic Airway Disease - Professor Hilary Pinnock

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Posted on January 22, Permalink. We are doing everything we can to help mitigate shortages of these products, especially ahead of the back-to-school season.

This change beyond the approved month shelf life is based on stability data provided by Mylan and ct asthma and allergy by the FDA. To help ensure patient safety, these products, ct asthma and allergy, which already have been dispensed to patients, should have been — and should continue to be — stored as labeled.

The FDA continues to work closely with Mylan on EpiPen production and supply, and also has been in contact ct asthma and allergy the other manufacturers of epinephrine auto-injectors, including Adrenaclick and Auvi-Q, regarding their supply as the school year begins since this is historically accompanied by increased product demand.

Posted on August 28, Permalink Comments 0. The FDA has granted Breakthrough Therapy designation to omalizumab Xolair, Genentecha subcutaneous injection therapy indicated for atopic ct asthma and allergy which could become the first treatment approved for the prevention of severe food allergy reactions.

Omalizumab was granted the designation to expedite its regulatory development and review as a potential therapy for serious or life-threatening conditions. Genentech and Novartis Pharmaceuticals are currently working with the NIAID and the Consortium of Food Allergy Research to launch a potentially pivotal study assessing the efficacy and safety of omalizumab in multiple food allergies, with details coming at a later date. Omalizumab was previously approved by the FDA to treat moderate to severe persistent asthma in patients aged 6 years or older whose asthma symptoms are not controlled by inhaled corticosteroids, as well as chronic idiopathic urticaria in patients 12 years and older who continue to have hives that are not controlled by H1 antihistamine treatment.

Up until now, avoidance has been the only treatment proven safe and effective for preventing allergic reactions to food. While oral immunotherapy is being studied, it is still considered experimental and not recommended by food allergy researchers or allergy societies.

Xolair offers the ability to reduce the likelihood of severe allergic reactions to foods without the risk associated with ingesting the food allergen daily, as is done in oral immunotherapy, which often triggers reactions including anaphylaxis, and carries the risk of complications such as eosinophilic esophagitis. We are hopeful that Xolair will obtain rapid approval for use in food allergies, and look forward to the protection and relief it will provide to amitriptyline and low blood sugar patients.

Posted on August 21, Permalink. Weakened by the common cold or the flu, a person suffering an asthma attack often responds poorly to emergency treatment; some must ct asthma and allergy hospitalized, ct asthma and allergy.

This is especially true for preschoolers. But what if there were a simple solution to help ward off the double whammy of an asthma attack and a respiratory virus? Well, there is one: Just over 1 in 10 Canadian children have asthma, aboutunder the age of The chronic disease often starts in early childhood—before age six years, in the preschool years.

Nose swabs were taken and analyzed to see if the children also had the flu or other respiratory viruses when they came to the ER. It turned out almost two-thirds did. Failure was also high in kids with respiratory syncytial virus RSV. By contrast, kids with strains of human rhinoviruses HRVs —the ct asthma and allergy cause of the common cold—did respond well to treatment for their asthma. To the researchers, this was very reassuring, ct asthma and allergy, as HRVs are the most frequent trigger of asthma attacks necessitating a visit to the ER.

We can start as young as age 6 months. Asthma is not usually diagnosed that early, but in Quebec every child who is diagnosed with asthma is eligible for influenza ct asthma and allergy. The problem is that not many parents are prevailing errin and generic of the opportunity. A major reason is access. This study is unique in that it quantifies the relation between treatment response and specific infections.

This study once again emphasizes the importance of influenza vaccination in all asthma patients. Our office offers influenza vaccination to all of our patients. Posted on June 05, Permalink Comments 0. Babies who are given antacids or antibiotics during their first 6 months of life may have a sharply higher risk for allergies or asthma, a large new study warns.

The finding is based on an analysis of health records of more thanct asthma and allergy, children born between and While the study does not prove that the medications cause allergy, lead author Dr. Edward Mitre said the links appear to be strong. That associated risk "appears substantial and clinically ct asthma and allergy Mitre added. Infant antacid exposure was linked to a doubling of the risk for developing food allergies, and a 50 percent increase in the risk for developing drug allergies and a hypersensitive immune reaction to foreign toxins, such as a bee sting anaphylaxis, ct asthma and allergy.

Mitre suspects "biological reasons" are at play. Evidence is mounting that changes in the microbiome can increase allergy risk. Antacids can reduce protein digestion in the stomach, Mitre explained, which may lead to food allergies. If an adult were to have to take in the same volume as an infant, it would be like drinking roughly two quarts every four hours. If I did that, I would be spitting up, too. Nyland said that, in most cases, ct asthma and allergy, feeding babies smaller and more frequent meals and burping them often is preferable to giving them antacids.

All were enrolled in the military health system within 35 days of birth and stayed enrolled for at least a year. Investigators looked at their early medication exposure and the onset of allergies and asthma over ct asthma and allergy average period of 4.

The study findings underscore well-known risks of antibiotics and counter the belief that acid-suppressives are harmless, Mitre said. While there are many infants who require these medications, and where the risk of not treating is far greater than the risk of treating, it is important that we consider potential adverse effects of medications, and weigh the risk vs.

Posted on April 13, Permalink. The women were all in the early stages of pregnancy with their first child. Around 10 percent of participants in the study reported that they had asthma.

Women treating their asthma with short-acting beta-agonists took on average 20 percent longer to conceive than women without asthma, or those using long-acting inhaled corticosteroids. Short-acting medication takers were also 30 percent more likely to take more than a year to conceive. Asthma is one of the most common conditions affecting women of reproductive age. Today, an estimated 5.

The relationship between asthma and fertility is not well understood. Both women and healthcare professionals have expressed concerns in the past about the safety of using medication to control asthma during pregnancy, ct asthma and allergy.

However, researchers have expressed concern about the interpretation of the results. Professor Kevin McConwaya statistician at the Open University who was not involved in the study, said in a statement: Further studies are planned for women undergoing fertility treatments to ct asthma and allergy if improving asthma control is able to improve fertility outcomes. Women with asthma who are planning pregnancy should continue their asthma control medications and speak with their physicians.

Posted on April 08, Permalink. They also reexamined the trials included in a systematic review. Both non-randomized and randomized controlled trials were examined for safety outcomes. Forty studies were included in total: Regarding safety, the authors observed that local and systemic allergic reactions were common, however anaphylaxis was rarely reported, ct asthma and allergy.

The authors concluded that "in children with allergic asthma, SCIT may reduce long-term asthma medication use. Posted on April 08, Permalink Comments 0.

A daily fish oil capsule taken after the 20th week of pregnancy and for the first three or four months of breastfeeding cut the chances of a child developing an egg allergy by 30 per cent, ct asthma and allergy, the research showed. Eczema risk was reduced by 22 per arthritis and silver in children whose mothers took a probiotic supplement between 36 and 38 weeks of pregnancy.

Adding beneficial bacteria to the diet during the first three to six months of breastfeeding had the same effect. The findings come from one of the biggest investigations of maternal diet and childhood allergy ever undertaken.

While clear benefits were seen from fish oil and probiotics, there was no evidence that avoiding potentially allergy-triggering foods such as nuts, dairy produce and eggs during pregnancy had any effect. A llergies to foods such as nuts, egg, milk or wheat affect around one in 20 children. They are the ct asthma and allergy of the immune system overreacting to harmless substances, leading to symptoms such as rashes, ct asthma and allergy, swelling, vomiting and wheezing.

E czema, also thought to involve an overactive immune response, affects around one in five children and ct asthma and allergy dry, cracked and itchy skin, ct asthma and allergy.

People who suffer from eczema are also more likely to have allergies. More work is needed to understand how fish oils and probiotics may protect against allergies and eczema, according to study co-author Dr Vanessa Garcia-Larsen, also from Imperial College.

The new findings appear in the latest issue of the online journal Public Library of Science Medicine. P revious studies have suggested that omega-3 fatty acids in fish oil may help to dampen down an overactive immune system.

Probiotics, taken in the form of capsules, a powder or a health drink, contain live bacteria that may influence the natural balance of microbes in the gut. Scientists have linked the disruption of naturally occurring gut "flora" to allergy risk. Commenting on the research, Seif Shaheen, professor of respiratory epidemiology at Queen Mary University of London, said: As always, discuss these and any other interventions with your obstetrician and pediatrician prior to implementing changes.

Posted on March 01, Permalink Comments 0. An experimental treatment aimed at helping people with severe peanut allergy recently scored a clinical win, putting it in line to possibly become the first drug to provide meaningful protection against accidental exposure.

Based on the positive results, ct asthma and allergy, Aimmune Therapeutics expects to seek U. The capsules are opened and mixed into food, ct asthma and allergy.

The idea is simple: Expose people to small, escalating doses of ingestible peanut protein over time with the goal of desensitizing them enough to prevent severe reactions. Aimmune is trying to standardize a peanut allergy protection method already tried on an ad hoc basis.

Six hundred milligrams of peanut protein is roughly the equivalent of two peanuts or a child-sized bite from a peanut butter sandwich. The patients entered the study not being able to tolerate exposure to 10 percent of a single peanut. To meet the FDA requirements for approval, AR had to beat placebo by a biostatistical cushion of at least 15 percent. Aimmune cleared this statistical hurdle easily with a 53 percent difference. There were some safety concerns in the study, ct asthma and allergy.

Twenty percent of the AR patients and 6.


Ct asthma and allergy